中国口腔颌面外科杂志

中国口腔颌面外科杂志 ›› 2021, Vol. 19 ›› Issue (5): 478-480.doi: 10.19438/j.cjoms.2021.05.018

• 病例报告 • 上一篇    

翼腭窝纤维黏液样梭形细胞瘤1例报告

石凡1, 薛然2, 周学筱1, 沈佩1, 徐婷3, 王升志3   

  1. 1.青岛大学口腔医学院,山东 青岛 266003;
    2.西安交通大学第一附属医院长安区医院 药学部,陕西 西安 710000;
    3.青岛大学附属烟台毓璜顶医院 口腔颌面外科,山东 烟台 266400
  • 收稿日期:2021-03-10 修回日期:2021-05-11 出版日期:2021-09-20 发布日期:2021-10-20
  • 通讯作者: 王升志,E-mail:wangsz916@163.com
  • 作者简介:石凡（1992-）,女,硕士研究生,E-mail：yifan610528@163.com

Fibromyxoid spindle cell tumor in the pterygopalatine fossa： a case report

SHI Fan1, XUE Ran2, ZHOU Xue-xiao1, SHEN Pei1, XU Ting3, WANG Sheng-zhi3   

  1. 1. School of Stomatology, Qingdao University. Qingdao 266003, Shandong Province;
    2. Department of Pharmacy, The First Affiliated Hospital of Xi 'an Jiaotong University, Chang'an District Hospital. Xi'an 710000, Shaanxi Province;
    3. Department of Oral and Maxillofacial Surgery, Affiliated Yantai Yuhuangding Hospital of Qingdao University. Yantai 264000, Shandong Province, China
  • Received:2021-03-10 Revised:2021-05-11 Online:2021-09-20 Published:2021-10-20

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摘要： 翼腭窝是位于上颌窦后壁和蝶骨翼突前表面之间的一小块区域,很少有肿瘤原发于翼腭窝。本文报告1例罕见的发生于翼腭窝的纤维黏液样梭形细胞瘤,并探讨其手术方案、治疗及预后。患者为58岁女性,CT显示右侧翼腭窝区呈结节状低密度影,增强CT显示翼腭窝区强化,边界不清,相邻的上颌窦壁强化,且与强化区相邻的上颌骨和右侧肌肉受压迫。组织病理学诊断为翼腭窝梭形细胞瘤,根据形态学特征确诊为骨结缔组织增生性纤维瘤,肿瘤周围有黏液样变性。免疫组织化学染色示CK(-), S-100(-), AE1/AE3(-), SMA(-), CD34(-), Des(-), MUC-4(-), p63(-), STAT-6(-),β-catering (nuclear -), Dog1(-),Ki-67阳性率为2%。

关键词: 翼腭窝, 梭形细胞瘤, 手术入路

Abstract: To report a rare case of fibromyxoid spindle cell tumor which occurred in the pterygopalatine fossa and discuss its imaging features, pathological diagnosis and treatment. A 58 years old female, CT showed nodular low-density mass in the right pterygopalatine fossa, enhanced CT showed mildly enhanced, with unclear boundaries, adjacent inferior wall of the right maxillary sinus was destructed, patchy enhanced shadow was seen in the posterior margin of the adjacent right maxilla and the right lateral muscle was oppressed. Spindle cell tumor of the right pterygopalatine fossa was confirmed under light microscopy. Morphological features were consistent with proliferative fibromas of bone connective tissue and mucous degeneration around the tumor. Immunohistochemistry showed that CK(-), S-100(-), AE1/AE3(-), SMA(-), CD34(-), Des(-), MUC-4(-), p63(-), STAT-6(-),β-catering (nuclear -), Dog1(-), the positive rate of Ki-67 was 2%.

Key words: Pterygopalatine fossa, Fibromyxoid spindle cell tumor, Operative approach

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